Vitamin C associated with decrease in postoperative atrial fibrillation – ProHealth

Reprinted with the kind permission of Life Extension.


February 03 2017. The results of a systemic review and meta-analysis published on February 1, 2017 in BMC Cardiovascular Disorders reveal an association between supplementation with vitamin C and a reduction in postoperative atrial fibrillation, a heart rhythm disturbance that can lead to stroke and heart failure which affects approximately 30% of cardiac surgery patients. The analysis also found a reduction in the length of hospital stay among vitamin C-treated patients.


Harri Hemilä of the University of Helsinki and Timo Suonsyrjä of Helsinki University Central Hospital reviewed 14 randomized trials involving a total of 2006 cardiac surgery patients and one trial that investigated atrial fibrillation recurrence following successful cardioversion (correction of cardiac arrhythmia) in 44 patients. The majority of trials administered vitamin C before and after surgery.


Nine trials, which were conducted outside of the US, revealed a risk of postoperative atrial fibrillation that averaged 44% lower among treated compared to untreated patients. Additionally, length of hospital stay was decreased by 12.6% and time spent in the intensive care unit was reduced by 8% in vitamin C treated patients in non-U.S. trials.  In the trial that examined the effect of vitamin C following cardioversion, there was an 87% reduction in atrial fibrillation recurrence in association with treatment.


While intravenous vitamin C was associated with a 36% decrease in postoperative atrial fibrillation, orally administered vitamin C was associated with a 73% reduction compared with untreated subjects. However, intravenously administered vitamin C was associated with a shorter hospital stay.


“Vitamin C is an essential nutrient that is safe and inexpensive,” the authors write. “Further research is needed to determine the optimal dosage protocol and to identify the patient groups that benefit the most.”

Comments

Write a Reply or Comment:

Your email address will not be published.*