If your doctor has recommended you regular exercising to improve the health of your cardiovascular system then you must also consider taking vitamin C pills. The best thing is that both these deliver the same results.
Lead author of this study, Caitlin Dow, PhD, postdoctoral research fellow at the University of Colorado, Boulder, conducted this research to see if vitamin C supplements can also reduce the endothelin-1 activity.
There were 35 obese volunteer adults. She and her team, then compared the effects of vitamin C and exercise on the protein known as endothelin-1, which has a constricting action on small blood vessels. Some of these participants were asked to walk or exercise daily and others were given Vitamin C supplements.
A meta-analysis of 44 clinical trials has shown a significant positive effect of vitamin C on endothelial function when taken at doses greater than 500 mg per day. The researchers noted that the effect of vitamin C supplementation appeared to be dependent on health status, with stronger effects in those at higher cardiovascular disease risk.
The protein activity increases in obesity struck people at night because of this high endothelin-1 activity, small vessels are more prone to constricting. This results in the blood vessels becoming less responsive to blood flow demand with an increase in the risk of vascular disease.
Researchers elaborated that walking or exercising can lower the endothelin-1 activity, however, people may not be able to follow a regular exercise schedule everyday. Another study confirmed that vitamin C consumption can decrease the risk of people with asthma developing exercise-induced bronchoconstriction.
The blood vessels of obese people showed elevated activity of the protein, ET-1. Those vessels with high ET-1 activity are more prone to constricting. This narrowing can mean blood vessels are less responsive to the changing demands on blood flow, therefore increasing a the risk of vascular disease.
Researchers observed that in both cases – daily exercisers and vitamin C takers – vasoconstriction to endothelin-1 increased two times. Results showed that daily supplementation of vitamin C at a time-release dose of 500 mg daily reduced endothelin-1-mediated vessel constriction as much as walking did.
Linus Pauling says, “I think we can get almost complete control of cardiovascular disease, heart attacks and strokes by the proper use of (vitamin C and lysine) … even cure it.”
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