Increased risk of heart failure associated with deficient levels of vitamin D – ProHealth

Reprinted with the kind permission of Life Extension.

August 25 2017. An article appearing on August 17, 2017 in ESC Heart Failure reported the finding of a strong association between increased heart failure risk and vitamin D deficiency among an older group of men and women.

For the current cross-sectional epidemiological study, researchers at Brazil’s Federal University of Pernambuco analyzed medical records from 137 subjects aged 60 years and older who were seen at cardiology outpatient clinics. Deficient vitamin D levels, defined as 25-hydroxyvitamin D levels less than 30 nanograms per milliliter (ng/mL), were revealed among 65% of the subjects.

Among vitamin D-deficient subjects, 78.7%, had an increased risk of heart failure as determined by Health and Aging and Body Composition Heart Failure scores that put them at medium, high, or very high risk in comparison with normal risk. “The increased risk of heart failure in this study was present in more than half of the elderly and was significantly associated with vitamin D deficiency (increasing by 12.2 times the risk of heart failure) and may be due to inflammatory mechanisms,” authors Catarina Magalhães Porto and colleagues reported.

“Based on the evidence presented in this study, which is supported by the literature, the high percentage of elderly individuals with vitamin D deficiency and its consequences for increased risk of heart failure suggest a need of dosage recommendations for this vitamin, especially in primary healthcare services,” they conclude. “The facility of quantifying vitamin D, the low cost of its supplementation, and the possibility of preventing and treating cardiovascular diseases point to the need for more studies on the supplementation with vitamin D in prospective cohort, so that the conduct of supplementation is implanted with a solid base of evidence.”


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